Proactol Fat Binding Study 2009 |
Abstract
2-Armed, Randomized, Double Blind, Placebo-Controlled Fat Excretion Study of the Patent Fibre Complex from Opuntia Ficus-Indica i.e. Proactol.
Introduction
Due to the high prevalence of obesity in industrialized countries, a reduction in body weight and calorie intake is of huge significance for health. Because of the high physiological calorific value of 9.3 Kcal/g, fat consumption accounts for the extra calorie intake.
The objective of this fat excretion study was to confirm increased fecal fat excretion after intake of the patent fibre complex in comparison to placebo, under the condition of standardized food intake.
Study Design
This 2-armed, randomized, double blind and placebo-controlled study was conducted in Berlin, Germany with Caucasian subjects in their own free-living surroundings. In order to reduce individual food intake variations, subjects were advised to adhere to a specified diet plan containing daily intake of 2500 kcal with a fat content of 30% (80g).
The effect of the Patent fibre complex on fat excretion, body weight, body mass index (BMI) and satiety were evaluated.
Study Results
- A. Fat Excretion
The Patent fibre complex from Opuntia Ficus-Indica significantly increased fecal fat excretion. After consumption of the Patent fibre complex, the fat absorption was reduced by up to 26.6%.
- B. Body Weight
After consumption of Proactol, there was an average reduction in body weight of 0.72 kg inside 3 days. In the placebo group there was no difference in the average body mass. This group difference is statistically significant.
- C. Feeling of Satiety
80% of subjects in the fibre complex arm reported a moderate (64%) or strong (16%) feeling of satiety. None of the subjects in the placebo arm reported similar feelings.
Conclusion
Compared to placebo, the Proactol significantly increased fecal fat excretion, reduced body weight (and BMI) and increased feeling of satiety. These were all achieved at the same time with a very good tolerability.
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